TRAM Biological Model

For this test, we used pre-processed gene expression values
as supplied by the Authors in the form of the Gene Expression Omnibus GSM data files.

In some cases the expression data were log2 transformed RMA signals (A1-A2 and B1-B6),
while in some other case the data were vsn transformed (B14-B19).

While this did not significantly affected the final results,
due to the use of non parametric statistics in the TRAM algorhitms,
it is advisable to use linear gene expression data when available,
as described in the TRAM software Guide.